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WebCaffeine and Hair Loss. The caffeine-induced inhibition of PDE enzymes increases intracellular cAMP concentrations, resulting in stimulatory effects on cell metabolism and proliferation. Hence, caffeine has a high potential to be beneficial in subjects suffering from hair loss that originates from premature termination of the hair growth phase . WebNational Center for Biotechnology Information WebFeb 17, 2024 · The caffeine in coffee stimulates these matrix cells to divide, which in turn, stimulates the growth of hair . Also, caffeine contains antioxidants that reduce trans … black ops arms nh