WebJul 15, 2011 · The Drosophila testis stem cell niche. Stromal hub cells (green) adhere to the apical tip of the testis. Surrounding the hub are germline stem cells (GSCs, yellow) and somatic cyst stem cells (CySCs, blue), which share the niche. GSCs and CySCs divide and produce daughter cells that remain in the niche (self-renewal) or leave the niche and ... WebMay 8, 2014 · One of the best characterized niches is found in the Drosophila testis apex, where a cluster of quiescent somatic cells called the hub creates a niche that maintains adjacent germline stem cells (GSCs) and somatic cyst stem cells (CySCs) (Figure 1A) (de Cuevas and Matunis, 2011).GSCs and CySCs divide asymmetrically, producing new …
Somatic CG6015 mediates cyst stem cell maintenance and …
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GitHub - ajfriend/cyscs: CySCS: A Cython wrapper for the …
WebSep 1, 2012 · Zfh-1 (red in Fig. 1C) is expressed at high levels in CySCs, fading rapidly in early stage cyst cells (cyst cells associated with proliferating germline cells). 10 Tj (green in Fig. 1C and D) is expressed at equal levels in CySCs and in early stage cyst cells. 11 Eya (red in Fig. 1D) shows a very low level of expression in early stage cyst ... WebImpL2 is expressed in CySCs to attenuate insulin signaling, while InR is expressed in CySCs and CCs, and is required for the onset of CC differentiation (Amoyel et al., 2016b) (Figures 4C-4D ... WebDec 20, 2024 · The CySCs of the male Drosophila requires the PI3K/target of rapamycin (Tor) activity to differentiate, and lack of which directs the CySCs into a proliferative state . In another study, centrosome misorientation was found to be the culprit of GSC loss or GSC proliferation delay caused by reduced insulin signalling or poor nutrition in male flies. covered pallet patio