Gli anticorpi anti-dsDNA, anche chiamati anti-DNA nativo, sono autoanticorpi antinucleo diretti contro la doppia elica del DNA (dsDNA è sigla dell'inglese double stranded DNA), associati a numerose malattie autoimmuni, in particolare al lupus eritematoso sistemico, dove sono presenti in oltre il 70% dei casi . Il valore plasmatico di tali anticorpi è inoltre correlato all'andamento clinico del LES . Web20 nov 2024 · UV-vis absorption spectra of 60 µM (A) MP and (B) IMI (1) before and (2) after incu with 10 µg mL −1 dsDNA in pH 7.0 0.1 M phosphate buffer after different exposure times to th simulator.
Cyclic GMP-AMP synthase is activated by double-stranded DNA ... - PubMed
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REF 41413 ZENIT RA dsDNA IgG - Menarini Diagnostics
Web17 nov 1986 · Anti-double stranded (ds) DNA antibodies in the sera of lupus-prone MRL/Mp-lpr/lpr (MRL/l) mice were determined by an enzyme-linked immunosorbent assay in parallel with anti-single stranded (ss) DNA, anti-left-handed Z-DNA and anti-poly(ADP-ribose) antibodies. The serum levels of these antibodies in … Web17 nov 1986 · Anti-double stranded (ds) DNA antibodies in the sera of lupus-prone MRL/Mp-lpr/lpr (MRL/l) mice were determined by an enzyme-linked immunosorbent assay in … Web2 giorni fa · Background: The presence of “anti-DNA antibodies in abnormal titres” is a well established criterion for SLE classification, but there is no agreement on the performance of this test. Objective: To study the correlation between clinical findings and five different solid and solution phase anti-DNA antibody assays. Methods: 158 consecutively collected … springfield mo elementary school map