WebJan 1, 2024 · Several drugs and toxins have been implicated as direct or indirect causes of a high-anion gap metabolic acidosis (HAGMA). A consideration of these drugs needs to be included in an differential diagnosis of a HAGMA. The three most common ones to consider are methanol, ethylene glycol and salicylates. Other toxins which can cause acidosis … WebMar 3, 2024 · Ingestion of ethylene glycol indirectly results in central nervous system compromise, cardiopulmonary depression, and renal failure 1 . Once absorbed from the gastrointestinal tract, which occurs rapidly, ethylene glycol is converted to glyoxylic acid and oxalic acid which are the compounds responsible for toxicity, and metabolic acidosis 1.

Ethylene glycol toxicity Radiology Reference Article Radiopaedia.org

Webacidosis is controlled, and. serum ethylene glycol level falls below 20 mg/dL. When renal function is preserved, patients often can be treated without hemodialysis. This outcome underscores the effectiveness of supportive care and the use of fomepizole in the treatment of ethylene glycol poisoning, even at levels that have traditionally ... WebJun 10, 2016 · Ethylene glycol, methanol, and diethylene glycol are readily available in many household and commercially available products. While these alcohols are relatively nontoxic themselves, their acidic metabolites are toxic and can result in significant morbidity and mortality. Herein we report a lethal case of massive ethylene glycol ingestion in a … google chrome offline installer windows 10

Orphanet: Ethylene glycol poisoning

WebNov 27, 2024 · Further, the treatment of ethylene glycol poisoning is aimed at blocking the formation of its toxic metabolites and the development of acidosis, for which the intravenous antidote is injected with ethylene glycol poisoning - ethanol or 4-methylpyrazole. In most cases, apply ethanol (ethyl alcohol): iv in 10 ml / kg 10% ethanol in 5% dextrose ... WebSep 26, 2024 · Ethylene glycol (C2H6O2) is a toxic alcohol that is found in various household and industrial agents. The term “toxic alcohols” is a collective term that includes methanol, ethylene glycol, and isopropyl alcohol. ... Ethylene glycol exposures can cause varying degrees of toxicity and management generally requires supportive care, close ... WebSep 17, 2024 · Propylene glycol intoxication (e.g. due to high intravenous doses of lorazepam, diazepam, nitroglycerine, esmolol, phenytoin) Nitroprusside (due to cyanide accumulation) Valproic acid, topiramate; Poisoning. Acetaminophen poisoning, massive; Alcohols Ethylene glycol (some assays will misidentify glycolic acid as lactic acid). … google chrome offline installer version 83