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WebApr 10, 2024 · Highlights: 1. IGFBP3 is induced by the crosstalk between TGF-β and EGFRvIII signaling in GBM cells. 2. EGFRvIII and IGFBP3 are overexpressed and positively correlated in GBM patients. 3. Inhibition of IGFBP3 effectively disturb the … WebNov 4, 2024 · The full economic cost (FEC) of your project can be up to £7,800,000. UK Research and Innovation (UKRI) will fund 80% of the FEC (up to £6,250,000). Funding is available for up to 40 months, with a fixed start date of 1 November 2024. You must be based at a UK research organisation to be eligible for UKRI funding. Opportunity status: … WebMar 9, 2024 · In this edition we look at two specific areas. First, we consider the revision of ICH Q2(R1) and the development of ICH Q14 as they have reached the key ICH milestone of Step 2 publication for public consultation. Second, we discuss the evolving and critical area of the environmental impact of the pharmaceutical industry, highlighting in particular the … cyril cusack actor